1019021-85-2

Basic information

• Product Name: 6-fluoroH-iMidazo[1,2-a]pyridin-3-carboxylic acid
• Synonyms: 6-fluoroH-iMidazo[1,2-a]pyridin-3-carboxylic acid;IMidazo[1,2-a]pyridine-3-carboxylic acid, 6-fluoro-
• CAS NO: 1019021-85-2
• Molecular Formula: C₈H₅FN₂O₂
• Molecular Weight: 184.1246032
• Mol File: 1019021-85-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Density: 1.53±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -1.00±0.41(Predicted)
• CAS DataBase Reference: 6-fluoroH-iMidazo[1,2-a]pyridin-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-fluoroH-iMidazo[1,2-a]pyridin-3-carboxylic acid(1019021-85-2)
• EPA Substance Registry System: 6-fluoroH-iMidazo[1,2-a]pyridin-3-carboxylic acid(1019021-85-2)

Safety Data

• Hazardous Substances Data: 1019021-85-2(Hazardous Substances Data)

Usage

General Description

6-fluoroH-imidazo[1,2-a]pyridin-3-carboxylic acid is a chemical compound with a molecular formula C8H5FN2O2. It is a heterocyclic compound that contains both a fluorine atom and a carboxylic acid functional group. 6-fluoroH-iMidazo[1,2-a]pyridin-3-carboxylic acid has potential applications in medicinal chemistry and drug development due to its heterocyclic structure, which has been found to exhibit biological activity. It may be used as a building block in the synthesis of pharmaceutical compounds or as a starting material for the development of new drugs. The presence of the fluorine atom in its structure may also impart specific properties or pharmacological activities to this compound.

Downstream Products

• 1426135-84-3 N-(5-cyano-2-methylphenyl)-6-fluoroimidazol[1,2-a]pyridine-3-carboxamide 
• 1426148-17-5 (Z)-6-fluoro-N-(5-(N'-hydroxycarbamimidoyl)-2-methylphenyl)-imidazol[1,2-a]pyridine-3-carboxamide 
• 1426666-28-5 6-fluoro-N-(5-(5-(3-hydroxy-3-methylbutyl)-1,2,4-oxadiazol-3-yl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide 
• 1426671-15-9 6-fluoro-N-(2-methyl-5-(5-(3-oxobutyl)-1,2,4-oxadiazol-3-yl)phenyl)imidazol[1,2-a]pyridine-3-carboxamide 
• 1426669-90-0 methyl (3-(3-(6-fluoroimidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)methylcarbamate 

Relevant articles and documents

SPIROCYCLOHEPTANES AS INHIBITORS OF ROCK

The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically-acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.

COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases.

COMPOUNDS AND COMPOSITIONS AS PDGFR KINASE INHIBITORS

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase