101909-42-6 Usage
General Description
1H-Indole-3-carboxylic acid, 4-chloro-, methyl ester is a chemical compound commonly used in organic synthesis and pharmaceutical research. It is a derivative of indole, a heterocyclic compound found in numerous natural products and biologically active molecules. The 4-chloro substitution on the indole ring and the ester functional group make this compound a versatile building block for the synthesis of various bioactive molecules. Its structure and reactivity also make it an attractive target for drug discovery and development, as it has the potential to exhibit diverse pharmacological activities. Overall, 1H-Indole-3-carboxylic acid, 4-chloro-, methyl ester serves as an important intermediate in the production of pharmaceuticals and organic compounds with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 101909-42-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,9,0 and 9 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 101909-42:
(8*1)+(7*0)+(6*1)+(5*9)+(4*0)+(3*9)+(2*4)+(1*2)=96
96 % 10 = 6
So 101909-42-6 is a valid CAS Registry Number.
101909-42-6Relevant articles and documents
The chemistry of indoles. XXIV. Syntheses of 3-indoleacetic acid and 3-indoleacetonitrile having a halogeno group and a carbon functional group at the 4-position
Somei,Kizu,Kunimoto,Yamada
, p. 3696 - 3708 (1985)
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A general and scalable synthesis of polysubstituted indoles
Diana-Rivero, Raquel,García-Tellado, Fernando,Tejedor, David
, (2021/06/14)
A consecutive 2-step synthesis of N-unprotected polysubstituted indoles bearing an electron-withdrawing group at the C-3 position from readily available nitroarenes is reported. The protocol is based on the [3,3]-sigmatropic rearrangement of N-oxyenamines generated by the DABCO-catalyzed reaction of N-arylhydroxylamines and conjugated terminal alkynes, and delivers indoles endowed with a wide array of substitution patterns and topologies.
