1019107-56-2

Basic information

• Product Name: (2S,4Z)-2-tert-butoxycarbonylamino-5-cyano-5-(2,3-difluorophenyl)pent-4-enoic acid methyl ester
• Synonyms: (2S,4Z)-2-tert-butoxycarbonylamino-5-cyano-5-(2,3-difluorophenyl)pent-4-enoic acid methyl ester
• CAS NO: 1019107-56-2
• Molecular Weight: 366.365
• Mol File: 1019107-56-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,4Z)-2-tert-butoxycarbonylamino-5-cyano-5-(2,3-difluorophenyl)pent-4-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4Z)-2-tert-butoxycarbonylamino-5-cyano-5-(2,3-difluorophenyl)pent-4-enoic acid methyl ester(1019107-56-2)
• EPA Substance Registry System: (2S,4Z)-2-tert-butoxycarbonylamino-5-cyano-5-(2,3-difluorophenyl)pent-4-enoic acid methyl ester(1019107-56-2)

Safety Data

• Hazardous Substances Data: 1019107-56-2(Hazardous Substances Data)

Upstream product

• 145689-34-5 2-(2,3-difluorophenyl)acetonitrile 
• 1019107-54-0 (S)-2-tert-butoxycarbonylamino-4-oxo-butyric acid ethyl ester 
• 74-88-4 methyl iodide 

Downstream Products

• 1019107-53-9 [(3S)-6-(2,3-difluorophenyl)-2-oxo-2,3,4,7-tetrahydro-1H-azepin-3-yl]carbamic acid tert-butyl ester 
• 1019107-59-5 C₁₇H₂₂F₂N₂O₃ 
• 1019107-57-3 C₁₈H₂₆F₂N₂O₄ 
• 1019107-60-8 C₁₈H₂₄F₂N₂O₄ 

Relevant articles and documents

Raney-co mediated reductive cyclization of an α,β-unsaturated nitrile

(Chemical Equation Presented) An expedient, five step synthesis of caprolactam 1 is reported starting from natural L-homoserine. The key step is a chemoselective reductive cyclization of α,β-unsaturated nitrile 10 mediated by Raney-Co type metals. This hydrogenation is extensively investigated in order to account for the observed product distribution and yields.