101913-37-5Relevant articles and documents
Synthesis and characterizations of flexible furfural based molecular receptor for selective recognition of Dy(III) ions
Kumar, Sandeep,Mohan, Brij,Sharma, Harish Kumar
, (2020)
Herein we report the development of a Dy(III) ion specific flexible molecular receptor incorporated with furan group. The capture experiment of several metal ions covering mono, di and trivalent metal ions with synthesized three molecules has been perform
Reworkable Polyhydroxyurethane Films with Reversible Acetal Networks Obtained from Multifunctional Six-Membered Cyclic Carbonates
Matsukizono, Hiroyuki,Endo, Takeshi
, p. 884 - 887 (2018)
Multifunctional 6-membered cyclic carbonates (6-CCs) comprising acetal structures have been synthesized via phosgene-free routes and utilized for the fabrication of reworkable networked poly(acetal-hydroxyurethane) (PAHU) films. Dibenzoyl-protected di(tri
1st generation dendrimeric antioxidants containing Meldrum's acid moieties as surface groups
Ai?pure, Klaudija,Jure, Māra,Mieri?a, Inese,Peipi?a, Elīna
, p. 607 - 620 (2022/01/22)
Free radical-caused oxidative stress can be reduced by various antioxidants. A new and promising type of antioxidant are monosubstituted Meldrum's acids. Herein the first dendritic architecture with 1,3-dioxane-4,6-dione units as surface groups is presented. The compounds were synthesized through the alkylation of phenol, the Knoevenagel condensation and sequential reduction. The antiradical activity (AA) against 1,1-diphenyl-2-picryl hydrazyl (DPPH) for all compounds is 80-90%, and the IC50 varies from 10-35 μM. These data are comparable with vitamin C, t-butylhydroquinone (TBHQ) or vitamin E. The AA against galvinoxyl (GO) increased with the number of surface groups. The AA was comparable with butylated hydroxytoluene (BHT) for compounds with at least two moieties of 1,3-dioxane-4,6-dione. The structure with a flexible glycerol core is highlighted among all the derivatives. Although the AA against DPPH for the glycerol derivative is comparable with those with aromatic cores it is more effective against GO (AA = 95%, IC50 = 60 μM): the AA is greater than for vitamin C and BHT. Thus, a flexible structure seems to be a promising core for elaborating powerful antioxidants with Meldrum's acid surface groups. This journal is
Synthesis, screening and in silico simulations of anti-parasitic propamidine/benzimidazole derivatives
Méndez-Cuesta, Carlos A.,Herrera-Rueda, Miguel ángel,Hidalgo-Figueroa, Sergio,Tlahuext, Hugo,Moo-Puc, Rosa,Chale-Dzul, Juan Bautista,Chan-Bacab, Manuel,Ortega-Morales, Benjamín Otto,Hernández-Nú?ez, Emanuel,Méndez-Lucio, Oscar,Medina-Franco, José L.,NavarreteVázquez, Gabriel
, p. 1 - 12 (2017/02/05)
Background: We designed hybrid molecules between propamidine and benzimidazole in order to retain the antiprotozoal action, but decreasing the toxic effect of the molecule. Objective: Design and prepare 12 hybrids for testing their antiparasitic effect ov
Synthesis and biological evaluation of conformationally flexible as well as restricted dimers of monastrol and related dihydropyrimidones
Kamal, Ahmed,Shaheer Malik,Bajee, Shaik,Azeeza, Shaik,Faazil, Shaikh,Ramakrishna, Sistla,Naidu,Vishnuwardhan
experimental part, p. 3274 - 3281 (2011/08/03)
A series of conformationally flexible and restricted dimers of monastrol as well as related dihydropyrimidones have been synthesized by employing one-pot Biginelli multicomponent reaction. These dimers have been evaluated for cytotoxic potency against sel
Efficient synthesis of alkylene bridging bisdihydropyridines
Liu, Dong-Mei,Du, Li-Ting,Sun, Jing,Yan, Chao-Guo
experimental part, p. 1333 - 1338 (2010/06/21)
Under microwave irradiation, vanillin was alkylated with α,W-dihaloalkane to give 4,4'-alkylene-bridging vanillins, which in turn underwent one-pot multicomponent reactions with excess of ethyl acetoacetate and ammonium bicarbonate to give 4,4'-alkoxy-bri
Facile and efficient synthesis of the dimers of DC-81 antitumor antibiotics
Kamal,Rao
, p. 4299 - 4302 (2007/10/02)
We report an improved, economical and versatile route to the dimers of DC-81 anti-tumour antibiotics. Particularly, the protection and deprotection steps in its synthesis and in the preparation of its precursors have been avoided. There is a significant i