101924-70-3Relevant articles and documents
One-pot enantiomeric synthesis of thiazole-containing amino acids: Total synthesis of venturamides A and B
Liu, Yi,He, Peng,Zhang, Yang,Zhang, Xiangyu,Liu, Jun,Du, Yuguo
, p. 3897 - 3905 (2018)
An effective one-pot procedure for enantiomerical synthesis of thiazole-containing amino acid (TCAA) has been established via a cascade disulfide cleavage/thiocarbonylation/intramolecular Staudinger reduction/aza-Wittig/oxidation reaction. Starting from the commercially available amino acid building blocks, a number of TCAAs were prepared in good yields and with excellent optical purities. This method bears features of mild reaction conditions, wide substrate adaptability, and good functional group tolerance. The power of this method was also demonstrated through the concise total synthesis of cyclic hexapeptide Venturamides A and B.
Total syntheses and re-assignment of configurations of the cyclopeptides lissoclinamide 4 and lissoclinamide 5 from Lissoclinum patella
Boden, Christopher D.J.,Pattenden, Gerald
, p. 875 - 882 (2007/10/03)
The total synthesis of lissoclinamide 4 and lissoclinamide 5, which are novel oxazoline/thiazole/thiazoline-based cyclopeptides isolated from the ascidian ("sea squirt") Lissoclinum patella, are described. The synthesis of the bis-thiazole based lissoclin
NEW METHODS AND REAGENTS IN ORGANIC SYNTHESIS. 55. TOTAL SYNTHESES OF PATELLAMIDES B AND C, CYTOTOXIC CYCLIC PEPTIDES FROM A TUNICATE 1. THEIR PROPOSED STRUCTURES SHOULD BE CORRECTED.
Hamada, Yasumasa,Shibata, Makoto,Shioiri, Takayuki
, p. 5155 - 5158 (2007/10/02)
Patellamides B and C, cytotoxic lipophilic cyclic peptides from a marine tunicate, with proposed structures have been synthesized by the use of diphenyl phosphorazidate(DPPA) and diethyl phosphorocyanidate(DEPC).Their physicochemical properties lead to re