1019331-10-2 Usage
Uses
Used in Pharmaceutical Industry:
S0859 is used as a selective inhibitor of sodium-bicarbonate cotransporters in mammalian heart for studying the role of NBC in various physiological and pathological processes. Its ability to block the sodium/bicarbonate cotransporter makes it a valuable tool in understanding the mechanisms underlying intracellular pH regulation and its impact on cardiac function.
Used in Research Applications:
S0859 is used as a research tool for investigating the role of NBC in different cell types, such as coronary endothelial cells, cancer cells, embryonic kidney cells, and neutrophils. This helps researchers to better understand the function of NBC in various biological processes and its potential as a therapeutic target for certain diseases.
Used in Drug Development:
S0859 serves as a lead compound in the development of new drugs targeting the sodium/bicarbonate cotransporter. Its selective inhibition of NBC makes it a promising candidate for the treatment of conditions related to intracellular pH dysregulation, such as certain types of cancer and cardiovascular diseases.
Biochem/physiol Actions
S0859 is a selective high-affinity generic inhibitor of the Na+/HCO3- sodium bicarbonate co-transporter (NBC). S0859 does not inhibit Na+-H+ exchange (NHE).
Check Digit Verification of cas no
The CAS Registry Mumber 1019331-10-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,9,3,3 and 1 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1019331-10:
(9*1)+(8*0)+(7*1)+(6*9)+(5*3)+(4*3)+(3*1)+(2*1)+(1*0)=102
102 % 10 = 2
So 1019331-10-2 is a valid CAS Registry Number.
