1019489-43-0Relevant articles and documents
Development of [3]ferrocenophane-derived N/B frustrated Lewis pairs for the metal-free catalytic hydrogenation of imines
Pan, Zhentao,Wang, Hui,Ling, Fei,Xiao, Lian,Song, Dingguo,Zhong, Weihui
, p. 522 - 528 (2019)
A series of novel [3]ferrocenophane-derived N/B frustrated Lewis pairs (FLPs) were synthesized and successfully applied to the catalytic hydrogenation of imines in 71–93% yields. This approach could be easily conducted on gram scale and provided versatile synthetic route for the key intermediate of sertraline hydrochloride without heavy metal residues.
Ansa-ferrocene derived tertiary amine, and preparation method and application thereof
-
Paragraph 0040, (2017/10/13)
The invention discloses ansa-ferrocene derived tertiary amine, and a preparation method and application thereof. The application is particularly as follows: the ansa-ferrocene derived tertiary amine and tri(pentafluorphenyl)boron according to the ratio of
Metal-free catalytic hydrogenation of imines with recyclable [2.2]paracyclophane-derived frustrated lewis pairs catalysts
Wang, Guan,Chen, Cheng,Du, Tieqi,Zhong, Weihui
supporting information, p. 1747 - 1752 (2014/06/09)
A series of [2.2]paracyclophane-derived frustrated Lewis pairs (FLPs) with reversible, metal-free hydrogen activation was synthesized and successfully applied in the hydrogenation of imines in moderate to good yields. The high stability of the novel FLP system enables effective recycling of the metal-free catalysts. This reaction could also be compatible with a larger scale and developed into a pharmaceutical synthesis of cinacalcet {(R)-N-[1-(1-naphthyl) ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine} without heavy metal residues.