10196-30-2

Usage

General Description

2-AMINO-2-METHYLBUTAN-1-OL, also known as 2-amino-2-methyl-1-butanol or α-aminoisobutyric acid, is a chemical compound with the molecular formula C5H13NO. It is a colorless, liquid organic compound with a slightly ammoniacal odor. This chemical is primarily used as a chiral building block in the synthesis of pharmaceuticals and agrochemicals. It is also used as a corrosion inhibitor and as a component in the production of polymers and resins. Additionally, 2-AMINO-2-METHYLBUTAN-1-OL has potential applications in fuel additives and as a solvent for a variety of organic compounds.

Upstream product

• 77392-55-3 2-methyl-2-nitro-butan-1-ol 
• 56247-82-6 α-ethylalanine ethyl ester 
• 1565-80-6 (2S)-2-methyl-1-butanol 
• 3059-97-0 (2R)-2-amino-2-methylbutanoic acid 
• 595-39-1 DL-isovaline 
• 563-46-2 2-Methyl-1-butene 

Relevant academic research and scientific papers

Electroorganic chemistry; 145: Coupling reaction of an olefin with a radical NO.3 generated by anodic oxidation of NO-3

When NO-3 is electrochemically oxidized in the presence of a variety of terminal and 1,2-disubstituted olefins 1 in a mixed solvent system (MeCN:H2O:Et2O = 10:2:1), a radical NO.3 is generated from NO-3 and nitrate esters 3 are formed by a new coupling reaction of the olefin with the radical. The products 3 can be further transformed into the corresponding alcohols 4 and alkyl iodides 5. Under the same reaction conditions, 1,1-di- and 1,1,2-trisubstituted olefins 6 do not give nitrate esters but afford oxazoline derivatives 7. (1S,5S)-(-)-β-Pinene (13) is diastereoselectively transformed into (1S,2R,5S)-(-)-myrtanol (14) by this technique.

NITRATED HYDROCARBONS, DERIVATIVES, AND PROCESSES FOR THEIR MANUFACTURE

Provided is a process for the formation of nitrated compounds by the nitration of hydrocarbon compounds with dilute nitric acid. Also provided are processes for preparing industrially useful downstream derivatives of the nitrated compounds, as well as novel nitrated compounds and derivatives, and methods of using the derivatives in various applications.

Palladium-catalyzed ring opening of isoprene monoxide with nitrogen nucleophiles - Asymmetric synthesis of branched amino sugars

The Pd-catalyzed regio- and enantioselective ring opening of isoprene monoxide with primary amines as pronucleophiles is developed with good yield and enantioselectivity, constructing a quaternary stereocenter enantioselectively. This methodology was used

Substituted pyridines

This invention relates to substituted pyridines prepared by reacting aldehydes, amines, lower carboxylic acids such as acetic acid in the presence of oxygen. The N-substituted pyridinium salts formed can be converted to pyridines by thermal dealkylation. The reactions can be summarized by the following equations: STR1