1019607-55-6

Basic information

• Product Name: 4-(cyclopropylamino)benzonitrile
• Synonyms: 4-(cyclopropylamino)benzonitrile
• CAS NO: 1019607-55-6
• Molecular Formula: C₁₀H₁₀N₂
• Molecular Weight: 158.1998
• Mol File: 1019607-55-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 321.6±25.0 °C(Predicted)
• Appearance: /Solid
• Density: 1.13±0.1 g/cm3(Predicted)
• PKA: 5.41±0.20(Predicted)
• CAS DataBase Reference: 4-(cyclopropylamino)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(cyclopropylamino)benzonitrile(1019607-55-6)
• EPA Substance Registry System: 4-(cyclopropylamino)benzonitrile(1019607-55-6)

Safety Data

• HazardClass: 6.1
• Hazardous Substances Data: 1019607-55-6(Hazardous Substances Data)

Upstream product

• 623-03-0 4-Cyanochlorobenzene 
• 765-30-0 Cyclopropylamine 
• 1194-02-1 4-fluorobenzonitrile 
• 623-00-7 4-bromobenzenecarbonitrile 

Downstream Products

• 1642594-54-4 C₁₈H₁₆N₂ 
• 1642594-57-7 C₁₄H₁₄N₂O₂ 
• 1610612-58-2 3-bromo-N-(4-cyanophenyl)-N-cyclopropylpyrazolo[1,5-a]pyridine-5-carboxamide 
• 1610611-56-7 N-(4-cyanophenyl)-N-cyclopropyl-3-(5-(methylcarbamoyl)pyridin-2-yl)pyrazolo[1,5-a]pyridine-5-carboxamide 
• 1610611-57-8 3-(5-carbamoylpyridin-2-yl)-N-(4-cyanophenyl)-N-cyclopropylpyrazolo[1,5-a]pyridine-5-carboxamide 

Relevant articles and documents

Nickel-Catalyzed N-Arylation of Cyclopropylamine and Related Ammonium Salts with (Hetero)aryl (Pseudo)halides at Room Temperature

Whereas the metal-catalyzed C(sp2)-N cross-coupling of cyclopropylamine with aryl electrophiles represents an attractive route to pharmaceutically relevant N-arylcyclopropylamines, few catalysts that are capable of effecting such transformation

COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES

The present invention provides compounds of formula I: [INSERT FORMULA HERE] or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a Plasmodium parasite, such as malaria.