101969-79-3 Usage
Synonyms
(R)-Adrenaline, 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-3-chloro-, (R)(9CI)
Chemical classification
Chemical compound
Structure
Contains a benzene ring with two hydroxyl groups (-OH) at the 1 and 2 positions, a chloro group (-Cl) at the 3 position, and an amino group (-NH2) attached to a hydroxyethyl group at the 4 position.
Function
Synthetic form of the hormone adrenaline
Produced by
Adrenal glands
Role
Neurotransmitter and hormone
Medical use
Treatment of shock, cardiac arrest, and anaphylaxis
Mechanism of action
Potent alpha and beta adrenergic agonist
Physiological effects
Increased heart rate and blood pressure, dilation of bronchial passages, increased blood flow to skeletal muscles
Adverse effects
Anxiety, tremors, and palpitations in some individuals
Check Digit Verification of cas no
The CAS Registry Mumber 101969-79-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,9,6 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 101969-79:
(8*1)+(7*0)+(6*1)+(5*9)+(4*6)+(3*9)+(2*7)+(1*9)=133
133 % 10 = 3
So 101969-79-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H10ClNO3/c9-7-4(6(12)3-10)1-2-5(11)8(7)13/h1-2,6,11-13H,3,10H2/t6-/m0/s1
101969-79-3Relevant academic research and scientific papers
Comparative α- and β-adrenoceptor activity of 2- and 6-ring-chlorinated noradrenaline analogues
Squier,Van der Schyf,Oliver,Venter
, p. 457 - 460 (2007/10/02)
The α- and β-adrenoceptor activity of the 2- and 6-ring-chlorinated analogues of noradrenaline (norepinephrine) were evaluated in vitro. The 2-chloro-substituted analogue exhibits a far greater affinity for β1-chronotropic receptors than the 6-chloro-substituted analogue, whereas no significant differences are apparent for their α-adrenergic affinities.
