1019691-75-8

Basic information

• Product Name: C₃₄H₃₆N₂O₄S
• Synonyms: C₃₄H₃₆N₂O₄S
• CAS NO: 1019691-75-8
• Molecular Weight: 568.737
• Mol File: 1019691-75-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₃₄H₃₆N₂O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₄H₃₆N₂O₄S(1019691-75-8)
• EPA Substance Registry System: C₃₄H₃₆N₂O₄S(1019691-75-8)

Safety Data

• Hazardous Substances Data: 1019691-75-8(Hazardous Substances Data)

Upstream product

• 71989-38-3 Fmoc-Tyr(tBu)-OH 

Downstream Products

• 1019691-23-6 Fmoc-Tyr(tBu)-Ala-Leu-OtBu 
• 71989-38-3 Fmoc-Tyr(tBu)-OH 

Relevant articles and documents

Incorporation of Acid-Labile Masking Groups for the Traceless Synthesis of C-Terminal Peptide α-Ketoacids

An optimized protocol for the masking of α-ketoacids with acid-labile cyclic acetal protecting groups is reported. Unlike prior approaches, these new conditions allow the synthesis of protected α-ketoacids bearing aromatic, hindered alkyl, and protected polar side chains. Attachment to a Wang-type linker and solid support provides a resin that delivers fully unprotected C-terminal peptide α-ketoacids upon resin cleavage. These peptides are the key starting materials for chemical protein synthesis using the α-ketoacid-hydroxylamine ligation.

Stereoretentive synthesis and chemoselective amide-forming ligations of C-terminal peptide α-ketoacids

C-Terminal peptide cyanosulfur ylides are readily converted to C-terminal peptide α-ketoacids, poised for chemoselective amide-forming reactions with hydroxylamines. These easily prepared and bench stable ylides are quickly and selectively oxidized with a