1019771-93-7

Basic information

• Product Name: 1-(diphenylmethyl)-3-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-1,3-dihydro-2H-indol-2-one
• Synonyms: 1-(diphenylmethyl)-3-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-1,3-dihydro-2H-indol-2-one
• CAS NO: 1019771-93-7
• Molecular Weight: 437.495
• Mol File: 1019771-93-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(diphenylmethyl)-3-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-1,3-dihydro-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(diphenylmethyl)-3-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-1,3-dihydro-2H-indol-2-one(1019771-93-7)
• EPA Substance Registry System: 1-(diphenylmethyl)-3-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-1,3-dihydro-2H-indol-2-one(1019771-93-7)

Safety Data

• Hazardous Substances Data: 1019771-93-7(Hazardous Substances Data)

Upstream product

• 150-19-6 O-methylresorcine 
• 94878-41-8 1-(diphenylmethyl)-1H-indole-2,3-dione 

Downstream Products

• 1019771-94-8 1-(diphenylmethyl)-3-(2-hydroxy-4-methoxyphenyl)-1,3-dihydro-2H-indol-2-one 

Relevant articles and documents

SPIROCYCLIC COMPOUNDS AS VOLTAGE-GATED SODIUM CHANNEL MODULATORS

The present invention relates to compounds of Formula (I) along with processes for their preparation that are useful for treating, preventing and/or managing the diseases, disorders, syndromes or conditions modulated by VGSCs. The invention further relates to methods of treating, preventing managing and/or lessening the diseases, disorders, syndromes or conditions by modulators of VGSC of Formula (I).

SPIRO COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS

This invention is directed to spiro-benzoisothiazole derivatives of formula (I), wherein j, k, m, q, Z, Q, R1, R2 and R3 are each as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of preparing and using the compounds are also disclosed.