101980-01-2Relevant academic research and scientific papers
An Asymmetric Synthesis of Chiral 4,4-Disubstituted Cyclohexenones in High Enantiomeric Purity
Meyers, A. I.,Lefker, Bruce A.,Wanner, Klaus Th.,Aitken, R. Alan
, p. 1936 - 1938 (2007/10/02)
An efficient approach to the title compounds in > 95percent ee has been accomplished by metalation and alkylation of chiral bicyclic lactams derived from δ-keto acids and (1S,2S)-2-amino-1-phenyl-1,3-propanediol.
