101999-46-6

Basic information

• Product Name: 2-(2-oxobenzo[h]chromen-4-yl)acetic acid
• CAS NO: 101999-46-6
• Molecular Formula: C₁₅H₁₀O₄
• Molecular Weight: 254.2375
• Mol File: 101999-46-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 531.7°C at 760 mmHg
• Flash Point: 209°C
• Density: 1.401g/cm³
• Vapor Pressure: 3.9E-12mmHg at 25°C
• Refractive Index: 1.679
• CAS DataBase Reference: 2-(2-oxobenzo[h]chromen-4-yl)acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-oxobenzo[h]chromen-4-yl)acetic acid(101999-46-6)
• EPA Substance Registry System: 2-(2-oxobenzo[h]chromen-4-yl)acetic acid(101999-46-6)

Safety Data

• Hazardous Substances Data: 101999-46-6(Hazardous Substances Data)

Upstream product

• 542-05-2 acetonedicarboxylic acid 
• 90-15-3 α-naphthol 
• 77-92-9 citric acid 
• 541-50-4 2-acetoacetic acid 
• 105-50-0 diethyl 1,3-acetonedicarboxylate 

Downstream Products

• 122448-00-4 4-(1-hydroxy-[2]naphthyl)-6-(2-methoxy-phenyl)-cyclohex-4-ene-1,2,3-tricarboxylic acid-1,2-anhydride-3-lactone 
• 122095-72-1 4-(2-methoxy-phenyl)-2-phenyl-3a,4,13a,13b-tetrahydro-benzo[7,8]chromeno[3,4-e]isoindole-1,3,13-trione 
• 133619-66-6 (+/-)-4-(1-hydroxy-[2]naphthyl)-6ξ-phenyl-cyclohex-4-ene-1r,2c,3ξ-tricarboxylic acid-1,2-anhydride-3-lactone 
• 118765-16-5 (+/-)-6ξ-(2-chloro-phenyl)-4-(1-hydroxy-[2]naphthyl)-cyclohex-4-ene-1r,2c,3ξ-tricarboxylic acid-1,2-anhydride-3-lactone 
• 1592738-14-1 (E)-4-[2-[2-(2-propyn-1-yloxyl)phenyl]ethenyl]-2H-naphtho[1,2-b]pyran-2-one 
• 110876-09-0 4-(2-methoxy-trans-styryl)-benzo[h]chromen-2-one 
• 133619-46-2 4-trans-styryl-benzo[h]chromen-2-one 
• 109979-25-1 4-(2-chloro-trans-styryl)-benzo[h]chromen-2-one 
• 128453-13-4 [2-Oxo-1-(4-phenylazo-phenyl)-1,2-dihydro-benzo[h]quinolin-4-yl]-acetic acid butyl ester 
• 128453-15-6 (2-Oxo-1-phenylamino-1,2-dihydro-benzo[h]quinolin-4-yl)-acetic acid N'-phenyl-hydrazide 
• 128453-16-7 2-(2-Oxo-1-p-tolyl-1,2-dihydro-benzo[h]quinolin-4-yl)-N-p-tolyl-acetamide 
• 128453-11-2 (1-Benzyl-2-oxo-1,2-dihydro-benzo[h]quinolin-4-yl)-acetic acid butyl ester 
• 128453-12-3 (2-Oxo-1-phenyl-1,2-dihydro-benzo[h]quinolin-4-yl)-acetic acid butyl ester 
• 128959-69-3 (Z)-3-(4-Nitro-phenyl)-2-(2-oxo-2H-benzo[h]chromen-4-yl)-acrylic acid butyl ester 

Relevant articles and documents

Synthetic and Structural Studies on Novel 4,3′-Bicoumarins

A series of directly linked 4-3′ bicoumarins have been synthesized by both Knoevenagel and Perkin reactions. This single-step transformation was accomplished by the reaction of coumarin-4-acetates with substituted salicylaldehydes in presence of piperidin

Facile intramolecular Diels-Alder reaction of 4-(o-propargyloxy) styrylcoumarins leading to highly fluorescent coumarin-containing polycyclic compounds

The 4-(o-propargyloxy)styrylcoumarins are prepared by the condensation of O-propargylated salicylaldehyde with substituted coumarin-4-acetic acids. The intramolecular Diels-Alder reaction of 4-(o-propargyloxy)styrylcoumarins, without any catalyst gives fu

Studies on synthesis of various N-substituted derivatives with different heterocycles and their herbicidal activity

Coumarin 4-methyl acetates are oxidized to coumarin-4- methyl glyoxalate using SeO2. Unlike the oxidative decaboxylation observed in the case of coumarin-4-acetic acid, here the oxidation is very selective for active methylene group, without affecting the COOH group protected with ester function. The product thus formed is analogous to the phenyl glyoxalic acid methyl ester i.e. coumarin 4-methyl glyoxalate and can be a useful moiety for the various synthetic manipulations of heterocycles substituted at 4-position of the coumarin showing promising herbicidal activity. Different heterocycles substituted at 4-position of the coumarin moiety have been synthesized. The herbicidal activity of these compounds has been evaluated. Zea Mays and Green Gram have been used for pre-emergence and postemergence screening of the herbicidal activity.