1020106-57-3Relevant academic research and scientific papers
Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H- pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor anta
Tseng, Shi-Liang,Hung, Ming-Shiu,Chang, Chun-Ping,Song, Jen-Shin,Tai, Chia-Liang,Chiu, Hua-Hao,Hsieh, Wan-Ping,Lin, Yinchiu,Chung, Wan-Ling,Kuo, Chun-Wei,Wu, Chien-Huang,Chu, Cheng-Ming,Tung, Yen-Shih,Chao, Yu-Sheng,Shia, Kak-Shan
experimental part, p. 5397 - 5412 (2009/07/01)
Replacing the conventional pyrazole 5-aryl substituent of 1 (SR141716A) with the 2-thienyl moiety appended with an appropriate alkynyl unit, a novel class of 5-(5-alkynyl-2-thienyl)pyrazole derivatives, behaving as highly potent CB1 receptor antagonists w
THIOPHENE COMPOUNDS
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Page/Page column 13, (2008/06/13)
This invention relates to thiophene compounds of formula (I) shown below: Each variable in formula (I) is defined in the specification. These compounds can be used to treat cannabinoid-receptor mediated disorders.
