102013-72-9

Usage

Uses

Used in Pharmaceutical Industry:
3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanoic acid is used as a building block for the synthesis of complex molecules, such as drugs and drug delivery systems, due to its ability to form stable amide bonds with primary amine groups.
Used in Cosmetics Industry:
3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanoic acid is used as an emulsifying agent and solubilizer in the formulation of cosmetics, taking advantage of its hydrophilic nature and ability to form stable bonds with other molecules.
Used in Research and Development:
3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanoic acid is used as a research tool for studying the properties and interactions of long-chain carboxylic acids, as well as their potential applications in various fields, including drug development and material science.
Used in Material Science:
3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanoic acid can be used as a component in the development of novel materials, such as hydrogels or polymers, due to its ability to form stable bonds and its hydrophilic nature.

Upstream product

• 6048-68-6 2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-ol 
• 25990-96-9 octaethylene glycol monomethyl ether 
• 79-11-8 chloroacetic acid 

Relevant academic research and scientific papers

o-Nitrobenzyl photoremovable groups with fluorescence uncaging reporting properties

o-Nitrobenzyl (o-NB) derivatives are the most widely applied photoremovable groups for the study of dynamic biological processes. By introducing different substituents to the benzylic position we were able to generate a fluorescence signal upon irradiatio

Grid coatings for capture of proteins and other compounds

Grids comprising a coating modified with one or more capture agents and a deactivating agent are disclosed. Methods of using such grids in connection with suitable microscopy techniques, such as for determining the structure of target compounds including proteins, are also disclosed.

CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS

Provided are conjugates of camptothecin analogs with a cell-binding molecule of formula (I), wherein R1, R2, R3, R4, R5, X, L, n, m, T and ----- are defined herein. It also provides methods of making the conjugates of camptothecin analogs to a cell-binding agent, as well as methods of using the conjugates in targeted treatment of cancer, infection, and immunological disorders.

CONJUGATION LINKERS CONTAINING 2,3-DIAMINOSUCCINYL GROUP

Provided is a conjugate of a cytotoxic drug/molecule to a cell-binding molecule with a bis-linker (adual-linker) containing a 2, 3-diaminosuccinyl group. It also relates to preparation of the conjugate of a cytotoxic drug/molecule to a cell-binding molecule with the bis-linker, particularly when the drug having functional groups of amino, hydroxyl, diamino, amino-hydroxyl, dihydroxyl, carboxyl, hydrazine, aldehyde and thiol for conjugation with the bis-linker in a specific manner, as well as the therapeutic use of the conjugates.

A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS

Provided herein is the conjugation of an amanita toxin compound to a cell-binding molecule with branched linkers for having better targeted treatment of abnormal cells. It also relates to a branched-linkage method of conjugation of an amanita molecule to a cell-binding ligand, as well as methods of using the conjugate in targets treatment of cancer, infection and autoimmune disease.

A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS

Provided is a conjugation of cytotoxic drug to a cell-binding molecule with a side-chain linker. It provides side-chain linkage methods of making a conjugate of a cytotoxic molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and immunological disorders.