1020172-05-7Relevant academic research and scientific papers
Ruthenium-catalyzed one-pot tandem isomerization-transfer hydrogenation reactions of γ-trifluoromethylated allylic alcohols and β-trifluoromethylated enones
Bizet, Vincent,Pannecoucke, Xavier,Renaud, Jean-Luc,Cahard, Dominique
supporting information, p. 1394 - 1402 (2013/07/19)
The ruthenium-2-propanol combination was found to transform γ-trifluoromethylated allylic alcohols and β-trifluoromethylated enones into the corresponding saturated alcohols in excellent yields via a one-pot tandem process involving isomerization and transfer hydrogenation(s). High stereospecificity was demonstrated and evidence for two mechanistic pathways is provided. The method was applied to a rapid synthesis of trifluoromethylated citronellol. Copyright
