1020186-11-1

Basic information

• Product Name: 2-{[(4-methoxybenzyl)oxy]methyl}cyclohex-2-en-1-one
• Synonyms: 2-{[(4-methoxybenzyl)oxy]methyl}cyclohex-2-en-1-one
• CAS NO: 1020186-11-1
• Molecular Weight: 246.306
• Mol File: 1020186-11-1.mol

Chemical Properties

• CAS DataBase Reference: 2-{[(4-methoxybenzyl)oxy]methyl}cyclohex-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[(4-methoxybenzyl)oxy]methyl}cyclohex-2-en-1-one(1020186-11-1)
• EPA Substance Registry System: 2-{[(4-methoxybenzyl)oxy]methyl}cyclohex-2-en-1-one(1020186-11-1)

Safety Data

• Hazardous Substances Data: 1020186-11-1(Hazardous Substances Data)

Upstream product

• 105956-40-9 2-(hydroxymethyl)cyclohex-2-en-1-one 
• 105-13-5 4-Methoxybenzyl alcohol 
• 937184-70-8 2-(4-methoxybenzyloxy)-4-methylquinoline 

Relevant articles and documents

Catalytic Direct Nucleophilic Substitution of Primary Morita-Baylis-Hillman Adducts and Application to the Straightforward Synthesis of Dihydroisoindolones

An interesting γ-carbonyl effect permits the dual iron/boron-catalyzed direct nucleophilic substitution of functionalized primary allylic alcohols with a large variety of nucleophiles. The resulting substitution products are useful synthetic platforms for heterocycle synthesis, as illustrated in a ready access to tetrahydroisoindol-4-ones.

An efficient means for generating p-methoxybenzyl (PMB) ethers under mildly acidic conditions

The protection of a wide variety of alcohols as their p-methoxybenzyl ethers can be performed with PMBO-lepidine in the presence of methyl tosylate or, preferably, camphorsulfonic acid. No inorganic promoters are required, thereby facilitating workup and product isolation. Georg Thieme Verlag Stuttgart.