1020267-70-2Relevant academic research and scientific papers
click synthesis of small-molecule inhibitors targeting caspases
Ng, Su Ling,Yang, Peng-Yu,Chen, Kitty Y.-T.,Srinivasan, Rajavel,Yao, Shao Q.
supporting information; experimental part, p. 844 - 847 (2008/10/09)
A panel of 198 P4-diversified aldehyde (reversible) and vinyl sulfone (irreversible) inhibitors is successfully synthesized via an efficient click chemistry platform and directly screened against caspase-3 and -7 for inhibition. The Royal Society of Chemistry.
