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102029-73-2 Usage


Acetyl coenzyme A sodium salt, also known as acetyl-CoA, is a crucial molecule in biological systems. It is the thioester of CoA and acetic acid, playing a central role as a source of carbon for the Krebs cycle, fatty acid synthesis, and isoprenoid-based protein modifications. Acetyl-CoA is also an intermediate in the oxidation of fatty acids and amino acids, formed by the oxidative decarboxylation of pyruvate in mitochondria. It acts as an essential cofactor or substrate for acetyltransferases and acyltransferases, involved in the post-translational modification of proteins and the synthesis of the neurotransmitter acetylcholine.


Used in Enzyme Assays:
Acetyl coenzyme A sodium salt is used as a substrate for assaying CAT enzyme activity in cell extracts using radioisotopes. The CAT enzyme activity in cell extracts catalyzes the transfer of acetyl groups from acetyl-CoA to chloramphenicol. Various assays have been developed to measure CAT activity in cell extracts.
Used in Citrate Synthase Activity Determination:
Acetyl coenzyme A sodium salt is also used to determine citrate synthase activity, which is an important enzyme in the Krebs cycle and plays a role in the regulation of cellular metabolism.

Biochem/physiol Actions

Acetyl-Coenzyme A (Ac-CoA) is the end product of glycolysis and takes part in the Ac-CoA pathway, which is a metabolic pathway for carbon compounds. Ac-CoA is important in cholesterol synthesis. It also takes part in fatty acid biosynthesis and catabolism of polyamines like spermine and spermidine. A low level of Ac-CoA leads to a loss in glial cell and neuronal function. Ketone bodies and triglycerides give rise to Ac-CoA on hydrolysis and this indirectly leads to increased histone acetylation.


Acetyl coenzyme A, the precursor of the acetate-malonare pathway, is a metabolite of extreme importance in both primary and secondary metabolism. In every living organism, there exists a metabolie pool of acetyl CoA which is continually replenished and depleted. Glycolysis and the catabolism of fatty acids and amino acids produce acetyl CoA, while this compound is the precursor of a host of primary and secondary metabolites, including fatty acids, terpenoids, steroids, polyketides, aromatic compounds and acetyl esters and amides. The conversion of acetyl CoA to citrate and other tricarboxylic acids leads to the formation of the amino acids and their products, such as the nucleic acids and alkaloids. Acetyl CoA is also central to the catabolism of glucose and the fatty acids, which, through the tricarboxylic acid cycle, are the main reaction sequences producing the energy necessary for metabolie processes. In plants, an enzyme, acetyl CoA synthetase, catalyses the formation of the thiol ester from acetate.

Check Digit Verification of cas no

The CAS Registry Mumber 102029-73-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,0,2 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 102029-73:
72 % 10 = 2
So 102029-73-2 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name Acetyl coenzyme A sodium salt

1.2 Other means of identification

Product number -
Other names Acetyl Coenzyme A

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:102029-73-2 SDS

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