102036-29-3

Basic information

• Product Name: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol
• Synonyms: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol;Protosappanin B;(7S,12aS)-7,8-Dihydro-7-(hydroxymethyl)-6H-dibenz[b,d]oxocin-3,7,10,11-tetrol
• CAS NO: 102036-29-3
• Molecular Formula: C₁₆H₁₆O₆
• Molecular Weight: 304.29500
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 102036-29-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 655.5±55.0 °C(Predicted)
• Appearance: /
• Density: 1.507
• Storage Temp.: 2-8°C
• PKA: 9.20±0.40(Predicted)
• CAS DataBase Reference: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol(102036-29-3)
• EPA Substance Registry System: (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol(102036-29-3)

Safety Data

• Hazardous Substances Data: 102036-29-3(Hazardous Substances Data)

Usage

General Description

The chemical compound (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol, also known as epicatechin, is a natural flavonoid found in various plants and foods, such as tea, grapes, and cocoa. It is a type of catechin, which is a class of polyphenolic compounds known for their antioxidant properties. Epicatechin has been studied for its potential health benefits, including its ability to support cardiovascular health, improve insulin sensitivity, and protect against oxidative stress. It is also being investigated for its potential anti-inflammatory and neuroprotective effects. As a result, epicatechin is of interest for its potential therapeutic applications in preventing and treating various chronic diseases.

Upstream product

• 111534-98-6 protosappanin C 
• 111830-78-5 C₁₉H₂₀O₆ 
• 111534-98-6 protosappanin C 
• 130233-78-2 protosappanin E 

Relevant articles and documents

Protosappanins E-1 and E-2, stereoisomeric dibenzoxocins combined with Brazilin from sappan lignum

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Protosappanin C from Sappan Lignum and Absolute Configuration of Protosappanins

A new dibenzoxocin derivative, named protosappanin C (3), C16H14O6, amorphous powder, 23D -39.8 deg (MeOH), was isolated from Sappan Lignum (the dried heart-wood of Caesalpina sappan L. (Leguminosae)).It yielded sappanin (4) on alkaline fusion, an oxime (5), a dimethyl acetal (6) on treatment with p-toluenesulfonic acid in methanol, and protosappanin B (2) on reduction with sodium borohydride.The circular dichroism spectra of 3 and 6 indicated that their biphenyl system preferentially takes S configuration, from which R configuration was assigned to C-7 of 3.On the basis of the above chemical and spectroscopic evidence, the chemical structure of 3 was established as (7R)-7,8-dihydro-3,7,10,11-tetrahydroxy-7(6H)-dibenzoxocincarbaldehyde.A possible route of biosynthesis of protosappanins from sappanchalcone is discussed.Keywords - Leguminosae; Caesalpina sappan; Sappan Lignum; dibenzoxocin; biphenyl; protosappanin C; sappanin; stereochemistry