1020576-70-8 Usage
General Description
Ethyl 6-bromoisoquinoline-1-carboxylate is a chemical compound used in the synthesis of various pharmaceuticals and organic compounds. It is a derivative of isoquinoline, a heterocyclic aromatic compound, and contains a bromine atom at position 6 of the isoquinoline ring. Ethyl 6-broMoisoquinoline-1-carboxylate has potential applications in medicinal chemistry and drug discovery due to its ability to modify the structure and activity of biologically active molecules. Additionally, it can be utilized as a building block in organic synthesis to create more complex molecules with specific medicinal or chemical properties. Its unique structure and reactivity make it a valuable tool in the field of chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 1020576-70-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,0,5,7 and 6 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1020576-70:
(9*1)+(8*0)+(7*2)+(6*0)+(5*5)+(4*7)+(3*6)+(2*7)+(1*0)=108
108 % 10 = 8
So 1020576-70-8 is a valid CAS Registry Number.
1020576-70-8Relevant articles and documents
Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene
Bass, Jonathan Y.,Caravella, Justin A.,Chen, Lihong,Creech, Katrina L.,Deaton, David N.,Madauss, Kevin P.,Marr, Harry B.,McFadyen, Robert B.,Miller, Aaron B.,Mills, Wendy Y.,Navas III, Frank,Parks, Derek J.,Smalley Jr., Terrence L.,Spearing, Paul K.,Todd, Dan,Williams, Shawn P.,Wisely, G. Bruce
, p. 1206 - 1213 (2011/04/16)
To improve on the drug properties of GSK8062 1b, a series of heteroaryl bicyclic naphthalene replacements were prepared. The quinoline 1c was an equipotent FXR agonist with improved drug developability parameters relative to 1b. In addition, analog 1c lowered body weight gain and serum glucose in a DIO mouse model of diabetes.
