10206-89-0 Usage
General Description
EXP561 is a chemical compound with the molecular formula C8H8NO2S. It is a pyrazolone derivative and is commonly used as a reagent in biochemical research and organic synthesis. EXP561 is known for its ability to inhibit the activity of glutathione reductase, an enzyme that plays a critical role in the maintenance of cellular redox balance. As a result, EXP561 is used to study the effects of glutathione reductase inhibition on cellular processes and to develop potential therapeutics for conditions associated with oxidative stress. Additionally, EXP561 has been investigated for its potential antioxidant and anti-inflammatory properties, making it a valuable tool for understanding the molecular mechanisms of redox regulation and for drug discovery efforts targeting oxidative stress-related diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 10206-89-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,0 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 10206-89:
(7*1)+(6*0)+(5*2)+(4*0)+(3*6)+(2*8)+(1*9)=60
60 % 10 = 0
So 10206-89-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H19N/c15-14-9-6-13(7-10-14,8-11-14)12-4-2-1-3-5-12/h1-5H,6-11,15H2
10206-89-0Relevant articles and documents
TRIAZOLOPYRIDINE INHIBITORS OF MYELOPEROXIDASE
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Page/Page column 71, (2017/10/18)
The present invention provides compounds of Formula (I). wherein A and Z are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and may be useful for for the treatment and/or prophylaxis of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.
