1020675-45-9Relevant academic research and scientific papers
Polyaminohydroxamic acids and polyaminobenzamides as isoform selective histone deacetylase inhibitors
Varghese, Sheeba,Senanayake, Thulani,Murray-Stewart, Tracey,Doering, Kim,Fraser, Alison,Casero Jr., Robert A.,Woster, Patrick M.
, p. 2447 - 2456 (2008)
A series of polyaminohydroxamic acids (PAHAs) and polyaminobenzamides (PABAs) were synthesized and evaluated as isoform-selective histone deacetylase (HDAC) inhibitors. These analogues contain a polyamine chain to increase affinity for chromatin and facil
