102069-44-3

Upstream product

• 137063-38-8 6''-O-acetyl-2,3,4,4',5',6',7',2'',3'',4''-deca-O-benzylvalidamycin D 
• 108-24-7 acetic anhydride 
• 102069-42-1 2,3,4',5',6',7'-hexa-O-acetyl-7-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)validoxylamine A 
• 102069-40-9 2,3,4',5',6',7'-hexa-O-acetylvalidoxylamine A 
• 86733-60-0 4,7-O-benzylidenevalidoxylamine A hexa-O-acetate 

Downstream Products

• 12650-67-8 validamycin D 

Relevant academic research and scientific papers

Synthetic Studies on Antiobiotic Validamycins. Part 14. Total Syntheses of (+)-Validamycins C, D and F

(+)-Validamycins C and F were first completely synthesised by use of a common blocked derivative 5 of (+)-validoxylamine A.The diols 6 and 7, obtained by acid hydrolysis of 5, were appropriately protected to give the aglycones 17, 25 and 30, which were co

Synthetic Studies on Antibiotic Validamycins. Part 11. Synthesis of Validamycin A

The antibiotic validamycin A (1a) has been synthesized for the first time (as its undeca-O-acetate) by glycosylation of the partially protected derivative (8) of the aglycone, validoxylamine A (2a), with 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl chloride (11), followed by deprotection, thereby establishing the structure previously assigned.The totally O-acetylated derivative (19) of 7-deoxyvalidamycin A has been synthesized in a similar fashion.