102069-93-2Relevant academic research and scientific papers
THE ENANTIOSELECTIVE CONVERSION OF ORTHO-SUBSTITUTED BENZOIC ACIDS TO CHIRAL CYCLOHEXANE DERIVATIVES
Schultz, Arthur G.,Sundararaman, Padmanabhan,Macielag, Mark,Lavieri, Frank P.,Welch, Martha
, p. 4575 - 4578 (2007/10/02)
The diastereoselectivity of reductive methylation of 1a-1c to give 2a-2c and 11 to give 12 is 260:1 and >99:1, respectively.
REDUCTIVE ALKYLATION OF 2-METHOXYBENZOIC ACID DERIVATIVES
Hook, James M.,Mander, Lewis N.,Woolias, Michael
, p. 1095 - 1098 (2007/10/02)
Metal-ammonia reduction followed by in situ alkylation of 2-methoxybenzoic acids often results in substantial loss of the methoxy substituent; reduction of the carboxylate salts or esters, however, supresses this side reaction and good to excellent yields
