1020737-23-8

Basic information

• Product Name: (4S)-4-(4-nitrobenzyl)-3-[(2E)-3-phenylprop-2-enoyl]-1,3-oxazolidin-2-one
• Synonyms: (4S)-4-(4-nitrobenzyl)-3-[(2E)-3-phenylprop-2-enoyl]-1,3-oxazolidin-2-one
• CAS NO: 1020737-23-8
• Molecular Weight: 352.346
• Mol File: 1020737-23-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S)-4-(4-nitrobenzyl)-3-[(2E)-3-phenylprop-2-enoyl]-1,3-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-4-(4-nitrobenzyl)-3-[(2E)-3-phenylprop-2-enoyl]-1,3-oxazolidin-2-one(1020737-23-8)
• EPA Substance Registry System: (4S)-4-(4-nitrobenzyl)-3-[(2E)-3-phenylprop-2-enoyl]-1,3-oxazolidin-2-one(1020737-23-8)

Safety Data

• Hazardous Substances Data: 1020737-23-8(Hazardous Substances Data)

Upstream product

• 102-92-1 Cinnamoyl chloride 
• 139264-55-4 (S)-4-(4'-nitrobenzyl)-1,3-oxazolidin-2-one 

Downstream Products

• 1020738-11-7 C₁₉H₁₈N₂O₇ 
• 1020738-09-3 C₁₉H₁₈N₂O₇ 

Relevant articles and documents

Diastereoselective ru-catalyzed cross-metathesis-dihydroxylation sequence. An efficient approach toward enantiomerically enriched syn-diols

(Chemical Equation Presented) Sequential catalysis has evolved as a powerful concept within the past years and allows the more efficient use of catalytically active expensive transition metals in organic synthesis. In this paper we present the stereoselective cross-metathesis-dihydroxylation of various olefins with chiral auxiliary substituted acrylamides. The chiral information (i.e., the auxiliary) introduced in the metathesis reactions allows for a stereoselective subsequent RuO4-catalyzed dihydroxylation. The sequence is concluded by an unusual kinetic resolution of the diastereomeric diols obtained in the oxidation reaction. As a consequence a variety of structurally diverse enantiomerically enriched diols are obtained. To the best of our knowledge the results summarized in this paper represent the first highly efficient diastereoselective RuO4-catalyzed oxidation.