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• 104-94-9 4-methoxy-aniline 
• 1571-08-0 methyl 4-formylbenzoate 
• 673855-94-2 methyl 4-{[(4-methoxyphenyl)imino]methyl}benzoate 

Relevant academic research and scientific papers

Nickel-catalysed reductive amination with hydrosilanes

That's just silyl! Selective nickel-catalyzed reductive amination of aldehydes under hydrosilylation conditions is achieved by using a one pot, two step procedure. By using an insitu-generated catalyst (5mol%) from Ni(OAc)2 and tricyclohexylphosphine with tetramethyldisiloxane (TMDS) as the hydrosilane at 70°C, the corresponding secondary amines were obtained in moderate to good isolated yields.

S-Benzyl isothiouronium chloride as a recoverable organocatalyst for the direct reductive amination of aldehydes

The direct reductive amination of aldehydes using S-benzyl isothiouronium chloride as a recoverable organocatalyst for the activation of the imine intermediate through hydrogen bonding is described. A mild and operationally simple fragment coupling procedure was accomplished with a wide range of aldehydes as well as amines in good to excellent yields. In addition, the S-benzyl isothiouronium chloride catalyst was easily recovered by simple filtration and reused without any drop in its efficiency.

Preparation method and application of metal organic ternary cyclic compound

The invention belongs to the technical field of fine chemical engineering, and relates to a preparation method and application of a metal organic ternary cyclic compound. In the preparation method, L is used as a ligand, Co2+ in transition metal cobalt salt is used as a node for reaction to prepare the metal organic ternary cyclic compound, and the synthesis route is as follows: L + Co2+ to Co-L; the metal organic ternary cyclic compound prepared by the method disclosed by the invention is novel in idea, good in reduction activity, stable in chemical property and easy for large-scale synthesis, so that the metal organic ternary cyclic compound is easier to put into practical application. The yield of the Co-DPD compound in the reaction of reducing 4-[(4-methoxyphenyl) iminomethyl] methyl benzoate into 4-[(4-methoxyphenyl) aminomethyl] methyl benzoate can reach 83%, and the yields of the Co-DPD compound used for preparing 4-[(4-methoxyphenyl) aminomethyl] benzonitrile and N-(4-methoxyphenyl)-4-(trifluoromethyl)-phenylethylamine can reach 95% and 80% respectively.

PHENYLETHYLPYRIDINE DERIVATIVES AS PDE4-INHIBITORS

The invention relates to novel compounds which are inhibitors of the phosphodiesterase 4 (PDE4) enzyme and muscarinic M3 receptor antagonists, methods of preparing such compounds, compositions containing them and therapeutic use thereof.

An easy and general iron-catalyzed reductive amination of aldehydes and ketones with anilines

A will of iron: An iron-catalyzed reductive amination of aldehydes and ketones with anilines using molecular hydrogen is presented. Under mild conditions, high yields for a broad range of aryl, alkyl, and heterocyclic ketones as well as aldehydes are achieved. Copyright