1020982-57-3Relevant academic research and scientific papers
Cyclometalated Half-Sandwich Iridium Complex for Catalytic Hydrogenation of Imines and Quinolines
Yao, Zi-Jian,Lin, Nan,Qiao, Xin-Chao,Zhu, Jing-Wei,Deng, Wei
, p. 3883 - 3892 (2018/11/24)
Several C,N-chelate cyclometalated half-sandwich iridium-based catalysts for imines and quinoline derivatives reduction have been prepared through metal-mediated C-H bond activation based on benzothiazole ligands. These iridium complexes exhibited high catalytic activity for hydrogenation of various types of imines with high yields. The most active catalyst was obtained from methoxyl substituted complex 2, showing the catalytic TOF value of 975 h-1 for the reduction of imine 6a. Additionally, these half-sandwich complexes also showed high efficiency for the catalytic hydrogenation of N-heterocyclic quinoline derivatives. Good catalytic activity was displayed for various kinds of substrates with either electron-donating or electron-withdrawing groups. Complexes 1-5 were fully characterized by NMR, IR, and elemental analysis. Molecular structures of complexes 1 and 4 were further confirmed by X-ray diffraction analysis.
Development of a general non-noble metal catalyst for the benign amination of alcohols with amines and ammonia
Cui, Xinjiang,Dai, Xingchao,Deng, Youquan,Shi, Feng
supporting information, p. 3665 - 3675 (2013/03/29)
The N-alkylation of amines or ammonia with alcohols is a valuable route for the synthesis of N-alkyl amines. However, as a potentially clean and economic choice for N-alkyl amine synthesis, non-noble metal catalysts with high activity and good selectivity are rarely reported. Normally, they are severely limited due to low activity and poor generality. Herein, a simple NiCuFeOx catalyst was designed and prepared for the N-alkylation of ammonia or amines with alcohol or primary amines. N-alkyl amines with various structures were successfully synthesized in moderate to excellent yields in the absence of organic ligands and bases. Typically, primary amines could be efficiently transformed into secondary amines and N-heterocyclic compounds, and secondary amines could be N-alkylated to synthesize tertiary amines. Note that primary and secondary amines could be produced through a one-pot reaction of ammonia and alcohols. In addition to excellent catalytic performance, the catalyst itself possesses outstanding superiority, that is, it is air and moisture stable. Moreover, the magnetic property of this catalyst makes it easily separable from the reaction mixture and it could be recovered and reused for several runs without obvious deactivation. Copyright
