1021002-43-6

Basic information

• Product Name: 2-(3,5-DiMethoxy-phenylaMino)-ethanol
• Synonyms: 2-(3,5-DiMethoxy-phenylaMino)-ethanol
• CAS NO: 1021002-43-6
• Molecular Formula: C₁₀H₁₅NO₃
• Molecular Weight: 197.231
• Mol File: 1021002-43-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3,5-DiMethoxy-phenylaMino)-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-DiMethoxy-phenylaMino)-ethanol(1021002-43-6)
• EPA Substance Registry System: 2-(3,5-DiMethoxy-phenylaMino)-ethanol(1021002-43-6)

Safety Data

• Hazardous Substances Data: 1021002-43-6(Hazardous Substances Data)

Usage

General Description

2-(3,5-DiMethoxy-phenylaMino)-ethanol is a chemical compound with the molecular formula C10H15NO3. It is a derivative of phenethylamine, a class of compounds known for their psychoactive effects. This particular compound is a di-substituted phenethylamine with two methoxy groups attached to the phenyl ring and an amino group attached to the ethyl chain. It is commonly used in research environments for its potential pharmacological and therapeutic properties, particularly in the field of neuroscience. Studies have shown that 2-(3,5-DiMethoxy-phenylaMino)-ethanol has the potential to affect neurotransmitter systems in the brain, making it a subject of interest for medicinal and scientific purposes.

Upstream product

• 107-21-1 ethylene glycol 
• 10272-07-8 3.5-dimethoxyaniline 
• 627-11-2 2-Chloroethyl chloroformate 

Downstream Products

• 1346245-09-7 N-(2-(((1,1-dimethylethyl)dimethylsilyl)oxy)ethyl)-3,5-dimethoxyaniline 
• 1346245-56-4 C₃₅H₅₀N₆O₅Si 
• 1346245-57-5 C₂₉H₃₆N₆O₅ 
• 1346245-58-6 C₃₀H₃₈N₆O₇S 
• 1346245-59-7 C₃₂H₄₃N₇O₄ 
• 1346245-63-3 C₃₆H₃₉N₇O₄ 
• 1346242-81-6 N¹-(3,5-dimethoxyphenyl)-N²-(1-methylethyl)-N¹-[3-(1-methyl-1H-pyrazol-4-yl)-6-quinoxalinyl]-1,2-ethanediamine 
• 1346253-27-7 C₃₂H₃₅N₇O₄ 
• 1346242-84-9 C₂₉H₃₄N₆O₄ 
• 1346242-86-1 C₂₂H₂₂IN₅O₂ 
• 1346242-85-0 C₂₈H₃₃N₇O₃ 
• 1346242-87-2 C₂₃H₂₆N₆O₃ 
• 1346242-88-3 C₂₆H₂₆N₆O₂ 
• 1346242-96-3 C₂₃H₂₆N₆O₂ 

Relevant articles and documents

β-Amino alcohols from anilines and ethylene glycol through heterogeneous Borrowing Hydrogen reaction

Borrowing Hydrogen (BH), also called Hydrogen Autotransfer (HA), reaction with neat ethylene glycol represents a key step in the preparation of β-amino alcohols. However, due to the stability of ethylene glycol, mono-activation has rarely been achieved. Herein, a combination of Pd/C and ZnO is reported as heterogeneous catalyst for this BH/HA reaction. This system results in an extremely air and moisture stable, and economic catalyst able to mono-functionalize ethylene glycol in water, without further activation of the diol. In this work, different diols and aromatic amines have been explored affording a new approach towards amino alcohols. This study reveals how the combination of two solid species can afford interesting catalytic properties in heterogeneous phase. ZnO activates ethylene glycol while Pd/C is the responsible of the BH/HA cycle. This catalytic system has also been found useful to dehydrogenate indoles affording indolines that undergo in situ BH/HA cycle prior to re-aromatization, representing a tandem heterogeneous process.