102103-81-1

Basic information

• Product Name: 1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, trans- (9CI)
• Synonyms: 1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, trans- (9CI)
• CAS NO: 102103-81-1
• Molecular Formula: C₈H₁₄O₃
• Molecular Weight: 158.19496
• Product Categories: ALDEHYDE
• Mol File: 102103-81-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, trans- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, trans- (9CI)(102103-81-1)
• EPA Substance Registry System: 1,3-Dioxolane-4-carboxaldehyde, 2,2,4,5-tetramethyl-, trans- (9CI)(102103-81-1)

Safety Data

• Hazardous Substances Data: 102103-81-1(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Fruity

Usage

Flavoring agent in the food industry

Application

Fragrance in cosmetic and personal care products

Function

Enhances aroma and taste of food and beverages

Additional use

Solvent in perfume manufacturing

Role

Chemical intermediate in the synthesis of other compounds

Safety concerns

Potential to irritate eyes, skin, and respiratory system

Precaution

Handle with care to avoid irritation

Upstream product

• 81875-77-6 (2RS,3SR)-methyl 2,3-isopropylidenedioxy-2-methylbutanoate 
• 106544-27-8 2-methyl-2-(1-hydroxy-1-methyl-3-phenylprop-2-en-1-yl)-1,3-dithiane 
• 106544-28-9 (2S,3RS)-2,3-dihydroxy-3-methyl-5-phenylpent-4-ene 
• 92010-40-7 3-hydroxy-3-methyl-5-phenylpent-4-en-2-one 
• 106544-30-3 (S)-2,2,4,5-Tetramethyl-4-((E)-styryl)-[1,3]dioxolane 
• 87826-86-6 methyl (+/-)-threo-2,3-dihydroxy-2-methylbutanoate 
• 6622-76-0 methyl (E)-2-methyl-2-butenoate 
• 104417-89-2 (2RS,3RS)-2,3-isopropylidenedioxy-2-methylbutan-1-ol 

Downstream Products

• 106622-94-0 (2S,3S,4R)-2,3-dihydroxy-3-methyl-4-(tosyloxy)hept-6-ene 
• 106544-36-9 (2S,3R,4S)-2,3-dihydroxy-3-methyl-4-(tosyloxy)hept-6-ene 
• 106544-38-1 Benzyl-carbamic acid (S)-1-((2S,3R)-3-allyl-2-methyl-oxiranyl)-ethyl ester 
• 106622-96-2 Benzyl-carbamic acid (S)-1-((2R,3S)-3-allyl-2-methyl-oxiranyl)-ethyl ester 
• 106544-35-8 Toluene-4-sulfonic acid 1-((S)-2,2,4,5-tetramethyl-[1,3]dioxolan-4-yl)-but-3-enyl ester 
• 106544-39-2 (4S,5S)-3-Benzyl-4-((S)-1-hydroxy-but-3-enyl)-4,5-dimethyl-oxazolidin-2-one 

Relevant articles and documents

Synthesis of pluraflavin A "aglycone"

The "aglycone" of pluraflavin A (2) has been synthesized. The key features of this synthesis include a 1,3-dipolar cycloaddition between a nitrile oxide (cf. 14) and an olefin (22) to yield an isoxazoline followed by subsequent conversion into the γ-pyrone of pluraflavin A. The epoxide moiety linked to the pyrone is installed prior to Diels-Alder installation of the D ring, which allows access to a number of potentially active cytotoxic intermediates en route to the final compound. The preliminary in vitro results of two such compounds are also included with the racemic title compound exhibiting cytotoxicity in the nanomolar range.

Stereochemistry and Synthetic Applications of the Products of Yeast Reduction of 3-Hydroxy-3-methyl-5-phenylpent-4-en-2-one

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