1021167-11-2

Basic information

• Product Name: (R(S),2S,3S,1'R)-N-(tert-butylsulfinyl)-2-(1-aminononyl)-3-ethylcyclohexanone
• Synonyms: (R(S),2S,3S,1'R)-N-(tert-butylsulfinyl)-2-(1-aminononyl)-3-ethylcyclohexanone
• CAS NO: 1021167-11-2
• Molecular Weight: 371.628
• Mol File: 1021167-11-2.mol

Chemical Properties

• CAS DataBase Reference: (R(S),2S,3S,1'R)-N-(tert-butylsulfinyl)-2-(1-aminononyl)-3-ethylcyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: (R(S),2S,3S,1'R)-N-(tert-butylsulfinyl)-2-(1-aminononyl)-3-ethylcyclohexanone(1021167-11-2)
• EPA Substance Registry System: (R(S),2S,3S,1'R)-N-(tert-butylsulfinyl)-2-(1-aminononyl)-3-ethylcyclohexanone(1021167-11-2)

Safety Data

• Hazardous Substances Data: 1021167-11-2(Hazardous Substances Data)

Upstream product

• 930-68-7 cyclohexenone 
• 1021167-07-6 (R)-2-methyl-N-nonylidenepropane-2-sulfinamide 
• 557-20-0 diethylzinc 

Relevant articles and documents

Tandem enantioselective conjugate addition-Mannich reactions: efficient multicomponent assembly of dialkylzincs, cyclic enones and chiral N-sulfinimines

A convenient access to enantiopure β-amino ketones through a multicomponent reaction of dialkyl zinc reagents, cyclic enones and chiral N-tert-butanesulfinimines is disclosed. Four diastereoisomers can be selectively obtained by the appropriate choice of the chiral ligand (L or ent-L) and the chiral N-sulfinimine (RS or SS). The protocol is particularly efficient when enolisable N-sulfinimines are used.

Modular stereoeontrolled assembly of R2Zn, cyclic enones and N-tert-butanesulfinyl imines

The assembly of a wide range of dialkylzincs, cyclic enones, and chiral N-tert-butylsulfinyl imines in the presence of the appropriate phosphoramidite ligands allowed the formation of β-amino ketones with three consecutive stereogenic centers in a stereoc