1021172-47-3

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 1391150-62-1 (E)-1-(4-bromophenyl)-7-(3-hydroxy-4-methoxyphenyl)hept-1-en-3-one 
• 76678-64-3 3-(3-benzyloxy-4-methoxyphenyl)acrylaldehyde 
• 621-59-0 isovanillin 
• 1021172-45-1 C₂₀H₂₁BrO₃ 

Relevant academic research and scientific papers

Microwave-assisted synthesis of macrocycles via intramolecular and/or bimolecular Ullmann coupling

Microwave-assisted synthesis of macrocyclic diaryl ethers via intramolecular and/or bimolecular Ullmann coupling is described. Using the optimized conditions, a panel of macrocycles, with different substitution patterns, ring sizes, and linkers, has been successfully synthesized using microwave irradiation. To the best of our knowledge, this work represents the first examples of the microwave-assisted synthesis of macrocyclic diaryl ethers via intramolecular and/or bimolecular Ullmann coupling.

Total synthesis of ovalifoliolatin B, acerogenins A and C

A short and concise route for the synthesis of ovalifoliolatin B, a highly strained macrocyclic diaryl ether heptanoid natural product that also provides quick access to acerogenins A and C natural products has been reported.