102139-89-9Relevant academic research and scientific papers
Substituent effects of ligands on asymmetric induction in a prototypical palladium-catalyzed allylation reaction: Making both enantiomers of a product in high optical purity using the same source of chirality
Clyne, Dean S.,Mermet-Bouvier, Yvan C.,Nomura, Nobuyoshi,RajanBabu
, p. 7601 - 7611 (1999)
The substituent effects of the ligands 1 through 8 play a crucial role in determining the enantioselectivity in the palladium-catalyzed asymmetric allylation reaction between 1,3-diphenylprop-2-en-1-yl acetate and the sodium salt of diethyl malonate. For
SYNTHESE CHIRALER PHOSPHINOXIDE UND PHOSPHINE DURCH MICHAELIS-ARBUZOV-UMLAGERUNG
Brunner, H.,Zettlmeier, W.
, p. 247 - 257 (2007/10/02)
Several phosphinites and phosphites, derived from chiral alcohols, were synthesized.The phosphinites were subjected to a I2-catalyzed Michaelis-Arbuzov rearrangement.Phosphinites derived from primary alcohols give satisfactory yields of the corresponding phosphineoxides.Phosphinites synthesized from secondary alcohols also undergo the rearrangement but numerous byproducts appear in the reaction mixtures.Optical resolutions of chiral phosphineoxides by crystallization with optically active acids were not successful.The corresponding phosphines can easily be prepared by reduction of the oxides with trichlorosilane.
