1021426-42-5

Basic information

• Product Name: 1-(4-(4-aMino-3-Methoxyphenyl)piperazin-1-yl)ethanone
• Synonyms: 1-(4-(4-aMino-3-Methoxyphenyl)piperazin-1-yl)ethanone;1-[4-(4-amino-3-methoxyphenyl)piperazin-1-yl]ethan-1-one;4-(4-acetyl-1-piperazinyl)-2- (methyloxy)aniline;1-[4-(4-amino-3-methoxyphenyl)-1-piperazinyl]-Ethanone;2-Methoxy-4-(4-acetylpiperazin-1-yl)benzenamine;2-methoxy-4-(4-acetylpiperazinyl)aniline;2-Methoxy-4-(n-acetyl-piperazin-1-yl)aniline
• CAS NO: 1021426-42-5
• Molecular Formula: C₁₃H₁₉N₃O₂
• Molecular Weight: 249.30886
• EINECS: -0
• Mol File: 1021426-42-5.mol
• Article Data: 22

Chemical Properties

• Melting Point: 131 °C
• Boiling Point: 495.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.185±0.06 g/cm3(Predicted)
• PKA: 7.63±0.10(Predicted)
• CAS DataBase Reference: 1-(4-(4-aMino-3-Methoxyphenyl)piperazin-1-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(4-aMino-3-Methoxyphenyl)piperazin-1-yl)ethanone(1021426-42-5)
• EPA Substance Registry System: 1-(4-(4-aMino-3-Methoxyphenyl)piperazin-1-yl)ethanone(1021426-42-5)

Safety Data

• Hazardous Substances Data: 1021426-42-5(Hazardous Substances Data)

Usage

General Description

1-(4-(4-Amino-3-Methoxyphenyl)piperazin-1-yl)ethanone is a chemical compound consisting of a piperazine ring with a 4-amino-3-methoxyphenyl group and an ethanone moiety. 1-(4-(4-aMino-3-Methoxyphenyl)piperazin-1-yl)ethanone is often used in research and laboratory settings as a reagent or building block for the synthesis of other chemicals. It may also have potential pharmacological or medical applications due to its structural features, such as its ability to interact with biological targets or exhibit biological activity. However, its specific uses and properties would need to be determined through further investigation and experimentation.

Upstream product

• 13889-98-0 N-acetylpiperidine 
• 1017782-79-4 tert-butyl 4-(3-methoxy-4-nitrophenyl)piperazine-1-carboxylate 
• 446-36-6 5-fluoro-2-nitrophenol 
• 448-19-1 4-fluoro-2-methoxy-1-nitrobenzene 
• 1116229-11-8 1-(4-{3-methoxy-4-nitrophenyl}piperazine-1-yl)ethan-1-one 

Downstream Products

• 1453198-89-4 1-[4-[4-[[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino]-3-methoxyphenyl]piperazin-1-yl]ethanone 
• 1453198-88-3 N-[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]acetamide 
• 1224704-62-4 1-[4-[4-[(5-fluoro-4-imidazo[1,2-a]pyridin-3-yl-pyrimidin-2-yl)amino]-3-methoxy-phenyl]piperazin-1-yl]ethanone 
• 1224705-35-4 1-[4-[4-[[5-chloro-4-(6-fluoroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]-3-methoxy-phenyl]piperazin-1-yl]ethanone 
• 1224705-22-9 3-[2-[[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino]-5-chloropyrimidin-4-yl]imidazo[1,2-a]pyridine-7-carbonitrile 
• 1224705-33-2 1-[4-[4-[[5-chloro-4-(7-chloroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]-3-methoxy-phenyl]piperazin-1-yl]ethanone 
• 1224705-24-1 1-[4-[4-[[5-chloro-4-(7-fluoroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]-3-methoxy-phenyl]piperazin-1-yl]ethanone 
• 1224705-25-2 1-[4-[4-[[5-chloro-4-(7-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]-3-methoxy-phenyl]piperazin-1-yl]ethanone 
• 1224705-26-3 1-[4-[4-[[5-chloro-4-(7-methoxyimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]-3-methoxy-phenyl]piperazin-1-yl]ethanone 
• 1224705-28-5 3-[2-[[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino]-5-chloropyrimidin-4-yl]imidazo[1,2-a]pyridine-8-carbonitrile 
• 1224705-29-6 1-[4-[4-[[5-chloro-4-(8-fluoroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]-3-methoxy-phenyl]piperazin-1-yl]ethanone 
• 1224705-27-4 1-[4-[4-[[5-chloro-4-[8-(hydroxymethyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-yl]amino]-3-methoxy-phenyl]piperazin-1-yl]ethanone 
• 1224705-30-9 1-[4-[4-[[5-chloro-4-(8-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]-3-methoxy-phenyl]piperazin-1-yl]ethanone 
• 1224705-31-0 1-[4-[4-[[5-chloro-4-(8-methoxyimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]-3-methoxy-phenyl]piperazin-1-yl]ethanone 

Relevant articles and documents

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TYROSINE KINASE NON-RECEPTOR 1 (TNK1) INHIBITORS AND USES THEREOF

Provided herein is a compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein values for the variables (e.g, X11, X22, R11, R22, R33, R44, R55, R66, R77, R88, m, n) are as described herein. Compounds of Formula I, pharmaceutically acceptable salts thereof, pharmaceutical compositions of either of the foregoing, and combinations of any of the foregoing can be used to treat tyrosine kinase non- receptor 1 (TNK1)-mediated diseases, disorders and conditions.