1021428-00-1

Basic information

• Product Name: (2S,3R)-N-benzyloxycarbonyl-3-hydroxypiperidine-2-carboxylic acid
• Synonyms: (2S,3R)-N-benzyloxycarbonyl-3-hydroxypiperidine-2-carboxylic acid
• CAS NO: 1021428-00-1
• Molecular Weight: 279.293
• Mol File: 1021428-00-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,3R)-N-benzyloxycarbonyl-3-hydroxypiperidine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3R)-N-benzyloxycarbonyl-3-hydroxypiperidine-2-carboxylic acid(1021428-00-1)
• EPA Substance Registry System: (2S,3R)-N-benzyloxycarbonyl-3-hydroxypiperidine-2-carboxylic acid(1021428-00-1)

Safety Data

• Hazardous Substances Data: 1021428-00-1(Hazardous Substances Data)

Upstream product

• 1021427-99-5 C₁₄H₁₇NO₄ 

Downstream Products

• 56879-47-1 (2R,3R)-3-hydroxypiperidine-1-carboxylic acis 

Relevant articles and documents

Chiron approach to the synthesis of (2S,3R)-3-hydroxypipecolic acid and (2R,3R)-3-hydroxy-2-hydroxymethylpiperidine from D-glucose

(Chemical Equation Presented) The first chiron approach from D-glucose for the total synthesis of (2S,3R)-3-hydroxypipecolic acid (-)-1a and (2R,3R)-3-hydroxy-2-hydroxymethylpiperidine (-)-2a is reported. The synthetic pathway involves conversion of D-glucose into 3-azidopentodialdose (5) followed by the Wittig olefination and reduction to give the piperidine ring skeleton (8) with a sugar appendage that on cleavage of an anomeric carbon followed by oxidation gives (-)-1a which on reduction affords (-)-2a.