1021456-82-5

Basic information

• Product Name: 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-
• Synonyms: Palonosetron USP RC B;Palonosetron Impurity 2;Palonosetron USP Impurity B;Dehydro N-Oxide Palonosetron;Dehydro palonosetron N-oxide;Palonosetron USP Related Compound B;Palonosetron USP Related Compound B HCl;Palonosetron Related Compound B (Palonosetron-3-ene N-Oxide);(S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine1-oxide;(S)-3-(1-oxo-5,6-dihydro-1H-benzo[de]isoquinolin-2(4H)-yl)quinuclidine 1-oxide HCl
• CAS NO: 1021456-82-5
• Molecular Formula: C19H22N2O2
• Molecular Weight: 310.39
• Mol File: 1021456-82-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• PKA: 4.72±0.40(Predicted)
• CAS DataBase Reference: 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-(1021456-82-5)
• EPA Substance Registry System: 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-(1021456-82-5)

Safety Data

• Hazardous Substances Data: 1021456-82-5(Hazardous Substances Data)

Usage

Description

Dehydro palonosetron N-oxide is a chemical compound related to palonosetron, which is a serotonin 5-HT3 receptor antagonist. It is an impurity found in the synthesis process of palonosetron and has potential applications in various industries due to its unique properties.

Uses

Used in Pharmaceutical Industry:
Dehydro palonosetron N-oxide is used as an impurity in the production of palonosetron, which is a crucial component for the development of antiemetic medications. Its presence in the synthesis process is significant for the pharmaceutical industry as it contributes to the overall effectiveness of palonosetron in preventing and treating chemotherapy-induced nausea and vomiting (CINV).
Used in Research and Development:
Dehydro palonosetron N-oxide can be utilized as a research compound for further investigation into its properties, potential applications, and possible improvements in the synthesis process of palonosetron. This can lead to the development of more effective antiemetic drugs and a better understanding of the compound's role in the pharmaceutical industry.
Used in Quality Control and Analysis:
In the manufacturing process of palonosetron, Dehydro palonosetron N-oxide can be used as a reference compound for quality control and analysis. By monitoring its presence and concentration, manufacturers can ensure the purity and efficacy of the final product, which is essential for the safety and effectiveness of the antiemetic medication.