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Benzenesulfonamide, 4-(chloromethyl)-, also known as 4-(chloromethyl)benzenesulfonamide or tosylmethyl chloride, is an organic compound with the chemical formula C7H7ClNO2S. It is a colorless to pale yellow crystalline solid that is soluble in water and various organic solvents. Benzenesulfonamide, 4-(chloromethyl)- is primarily used as a reagent in organic synthesis, particularly in the preparation of various pharmaceuticals, agrochemicals, and other specialty chemicals. It is also employed as a protecting group in peptide synthesis and as a coupling agent in the formation of amide bonds. Due to its reactivity, it is essential to handle this chemical with care, as it can be harmful if inhaled, ingested, or absorbed through the skin.

102153-43-5

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102153-43-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 102153-43-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,1,5 and 3 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 102153-43:
(8*1)+(7*0)+(6*2)+(5*1)+(4*5)+(3*3)+(2*4)+(1*3)=65
65 % 10 = 5
So 102153-43-5 is a valid CAS Registry Number.

102153-43-5Relevant academic research and scientific papers

Synthesis and Inhibitory Activity on Carbonic Anhydrase of Some New Sulpiride Analogues Studied by Means of a New Method

Botre, Claudio,Botre, Francesco,Jommi, Giancarlo,Signorini, Roberto

, p. 1814 - 1820 (2007/10/02)

The pharmacological activity of several new sulpiride analogues was studied by means of a new approach, based on a potentiometric technique with a pCO2 sensor, capable of detecting carbonic anhydrase inhibition at equilibrium conditions.This procedure gives results stated as percent of inhibition of enzymatic activity (IP, inhibitory power).To prove the reliability of the proposed approach and to study structure-activity relationships, several new molecules were synthesized and tested in comparison with the two sulpiride enantiomers.A possible inhibition mechanism is discussed in terms of experimental evidence obtained from the interactions between the molecular structures of the new synthesized compounds and carbonic anhydrase.

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