102168-71-8Relevant academic research and scientific papers
Modification of estrone at the 6, 16, and 17 positions: Novel potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1
Allan, Gillian M.,Lawrence, Harshani R.,Cornet, Josephine,Bubert, Christian,Fischer, Delphine S.,Vicker, Nigel,Smith, Andrew,Tutill, Helena J.,Purohit, Atul,Day, Joanna M.,Mahon, Mary F.,Reed, Michael J.,Potter, Barry V. L.
, p. 1325 - 1345 (2007/10/03)
The 17β-hydroxysteroid dehydrogenases (17β-HSDs) catalyze the interconversion between the oxidized and reduced forms of androgens and estrogens at the 17 position. The 17β-HSD type 1 enzyme (17β-HSD1) catalyzes the reduction of estrone to estradiol and is
