102170-53-6

Basic information

• Product Name: 4-Bromo-3-chloro-6-methoxyaniline
• Synonyms: 4-Bromo-3-chloro-6-methoxyaniline;4-BroMo-5-chloro-2-Methoxyaniline
• CAS NO: 102170-53-6
• Molecular Formula: C₇H₇BrClNO
• Molecular Weight: 236.49358
• Mol File: 102170-53-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 296.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.643±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 2.78±0.10(Predicted)
• CAS DataBase Reference: 4-Bromo-3-chloro-6-methoxyaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-3-chloro-6-methoxyaniline(102170-53-6)
• EPA Substance Registry System: 4-Bromo-3-chloro-6-methoxyaniline(102170-53-6)

Safety Data

• Hazardous Substances Data: 102170-53-6(Hazardous Substances Data)

Usage

Uses

4-Bromo-5-chloro-2-methoxyaniline is a versatile reactant used in the preparation of thiazole and thiophene derivatives as store-operated calcium channels modulators useful in treatment of SOC channel-mediated diseases.

Upstream product

• 89-61-2 2,5-dichloronitrobenzene 
• 95-03-4 5-chloro-2-methoxyaniline 
• 89-21-4 4-chloro-2-nitroanisole 

Downstream Products

• 5579-85-1 5,7-dibromo-6-hydroxy-2H-1,3-benzoxathiol-2-one 
• 1613730-70-3 4-amino-2-chloro-5-methoxy-3-((trimethylsilyl)ethynyl)benzonitrile 
• 1613730-69-0 4-amino-2-chloro-3-iodo-5-methoxybenzonitrile 
• 1613730-68-9 4-amino-2-chloro-5-methoxybenzonitrile 
• 1366109-75-2 C₁₉H₁₂ClFN₂O₂Se 
• 1361379-08-9 [5-(5-chloro-2-methylbenzoxazol-6-yl)(2-thienyl)]-N-(2,6-difluorophenyl)carboxamide 
• 1361379-07-8 [5-(5-chloro-2-methylbenzoxazol-6-yl)(2-thienyl)]-N-(2-fluorophenyl)carboxamide 
• 1361379-06-7 [5-(5-chloro-2-methylbenzoxazol-6-yl)(2-thienyl)]-N-(2-chlorophenyl)carboxamide 
• 1346667-63-7 N-[4-(5-chloro-2-methylbenzoxazol-6-yl)phenyl](3-fluoro(4-pyridyl))carboxamide 
• 1346665-53-9 4-(5-chloro-2-methylbenzoxazol-6-yl)phenylamine 
• 1346665-54-0 N-[4-(5-chloro-2-methylbenzoxazol-6-yl)phenyl](2-fluorophenyl)carboxamide 
• 1345117-89-6 N-[5-(5-chloro-2-methylbenzoxazol-6-yl)(2-pyridyl)](2-chlorophenyl)carboxamide 
• 40372-61-0 2-amino-5-bromo-4-chlorophenol 
• 1345117-76-1 N-[5-(5-chlorobenzoxazol-6-yl)(2-pyridyl)](2-chlorophenyl)carboxamide 

Relevant articles and documents

3-(6-CHLORO-3-OXO-3,4-DIHYDRO-(2H)-1,4-BENZOXAZIN-4-YL) PROPANOIC ACID DERIVATIVES AND THEIR USE AS KMO INHIBITORS

Compounds of formula (I) wherein: R1 is heteroaryl optionally substituted by methyl, ethyl, halo or =O; and R2 is H, methyl or ethyl. and salts thereof are KMO inhibitors and may be useful in the treatment of various disorders, for example acute pancreatitis, chronic kidney disease, other conditions associated with systemic inflammatory response syndrome (SIRS), Huntington's disease, Alzheimer's disease, spinocerebellar ataxias, Parkinson's disease, AIDS-dementia complex, HIV infection, amylotrophic lateral sclerosis (ALS), depression, schizophrenia, sepsis, cardiovascular shock, severe trauma, acute lung injury, acute respiratory distress syndrome, acute cholecystitis, severe burns, pneumonia, extensive surgical procedures, ischemic bowel disease, severe acute hepatic disease, severe acute hepatic encephalopathy or acute renal failure.