102181-30-6

Basic information

• Product Name: N-(2-(1H-indol-3-yl)ethyl)-4-phenylbutanamide
• Synonyms: N-(2-(1H-indol-3-yl)ethyl)-4-phenylbutanamide
• CAS NO: 102181-30-6
• Molecular Weight: 306.407
• Mol File: 102181-30-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2-(1H-indol-3-yl)ethyl)-4-phenylbutanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(1H-indol-3-yl)ethyl)-4-phenylbutanamide(102181-30-6)
• EPA Substance Registry System: N-(2-(1H-indol-3-yl)ethyl)-4-phenylbutanamide(102181-30-6)

Safety Data

• Hazardous Substances Data: 102181-30-6(Hazardous Substances Data)

Upstream product

• 61-54-1 tryptamine 
• 1821-12-1 4-Phenylbutyric acid 

Downstream Products

• 110530-79-5 1-(3-phenyl-propyl)-2,3,4,9-tetrahydro-1H-β-carboline 
• 102947-63-7 1-(3-phenyl-propyl)-4,9-dihydro-3H-β-carboline 

Relevant articles and documents

Direct synthesis of amides from carboxylic acids and amines using B(OCH2CF3)3

B(OCH2CF3)3, prepared from readily available B2O3 and 2,2,2-trifluoroethanol, is as an effective reagent for the direct amidation of a variety of carboxylic acids with a broad range of amines. In most cases, the amide products can be purified by a simple filtration procedure using commercially available resins, with no need for aqueous workup or chromatography. The amidation of N-protected amino acids with both primary and secondary amines proceeds effectively, with very low levels of racemization. B(OCH2CF3)3 can also be used for the formylation of a range of amines in good to excellent yield, via transamidation of dimethylformamide.