102184-30-5Relevant articles and documents
Novel method of synthesizing various five membered heterocycles from an aryl tribromomethyl group
Tynebor, Robert,Millings, Elizabeth
, p. 1902 - 1908 (2013/05/21)
Synthesis of five membered heterocycles from an aryl tribromomethyl functional group is discussed. Exposing a tribromomethyl group to subsequent nucleophilic attacks by a 1,2-di-nucleophilic species promotes the cyclization of five membered heterocycles. Such heterocycles as oxadiazoles, thiadiazole, benzimidazole, benzothioazole, and benzoxazole were synthesized in moderate to good yields. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications to view the free supplemental file.