1021949-90-5Relevant academic research and scientific papers
Selective synthesis of fluorinated benzyl- or phenylpyrimidines from the heterocyclisation of α-trifluoroacetylarylpropanenitriles
Berber, Hatice,Mirand, Catherine,Derouin, Francis
, p. 1039 - 1045 (2008/02/10)
Some 5-benzyl-6-trifluoromethyl-2,4-diaminopyrimidines analogous to trimethoprim and 6-aryl-5-trifluoroethyl-2,4-diaminopyrimidines analogous to pyrimethamine were prepared from the same synthons, trifluoromethylated β-ketonitriles. The heterocyclisation
