1021950-18-4 Usage
Classification
Pyrrolopyridine-based small molecule inhibitors.
Structure
Ethyl ester derivative of 4-(4-aminophenoxy)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid.
Target enzymes
Potent inhibitor of DNA methyltransferases (DNMTs) and histone methyltransferases (HMTs).
Biological activity
Shown promising anticancer and antiviral activity in preclinical studies.
Therapeutic potential
Investigation for treatment of various cancers, viral infections, and diseases related to aberrant gene methylation and histone modifications.
Epigenetic therapy
Has the potential to be developed into a valuable drug candidate for targeted epigenetic therapy.
Check Digit Verification of cas no
The CAS Registry Mumber 1021950-18-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,1,9,5 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1021950-18:
(9*1)+(8*0)+(7*2)+(6*1)+(5*9)+(4*5)+(3*0)+(2*1)+(1*8)=104
104 % 10 = 4
So 1021950-18-4 is a valid CAS Registry Number.
1021950-18-4Relevant academic research and scientific papers
NOVEL COMPOUNDS
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Page/Page column 41, (2008/12/05)
The present invention relates to compounds of formula (I): and processes for preparing them, compositions containing them and their use in treating diseases relating to inappropriate c-Met activity.