1022091-46-8

Usage

Derived from

Quinoline (a heterocyclic compound)

Contains

A quinolinyl group and an acetic acid group

Type of compound

Organic acid

Potential use

Building block for the synthesis of pharmaceuticals and other biologically active molecules

Molecule of interest

Difluoroquinoline moiety (for potential pharmacological properties)

Chemical modification handle

Acetic acid group

Possible applications

Medicinal chemistry and drug discovery

Upstream product

• 1022091-51-5 2-(5,7-difluoro-quinolin-6-yl)-malonic acid diethyl ester 
• 1001755-64-1 2-(4-amino-2,6-difluorophenyl)acetic acid 
• 56-81-5 glycerol 

Downstream Products

• 1086331-60-3 methyl 2-(5,7-difluoroquinolin-6-yl)acetate 

Relevant academic research and scientific papers

NOVEL 3,5-DISUBSTITUTED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUTED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES

The present invention provides, inter alia, compounds of formula I as protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.

NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES

The present invention provides, inter alia, compounds of formula ΙΑ,ΙΙΑ and III as protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.

HETEROCYCLIC KINASE MODULATORS

The present disclosure provides heterocyclic protein kinase modulators and methods of using these compounds to treat diseases mediated by kinase activity.