1022112-31-7

Basic information

• Product Name: methyl 2-(2-fluoro-3-hydroxy-6-nitrophenyl)-3-oxobutanoate
• Synonyms: methyl 2-(2-fluoro-3-hydroxy-6-nitrophenyl)-3-oxobutanoate
• CAS NO: 1022112-31-7
• Molecular Weight: 271.202
• Mol File: 1022112-31-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-(2-fluoro-3-hydroxy-6-nitrophenyl)-3-oxobutanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2-fluoro-3-hydroxy-6-nitrophenyl)-3-oxobutanoate(1022112-31-7)
• EPA Substance Registry System: methyl 2-(2-fluoro-3-hydroxy-6-nitrophenyl)-3-oxobutanoate(1022112-31-7)

Safety Data

• Hazardous Substances Data: 1022112-31-7(Hazardous Substances Data)

Upstream product

• 1022112-29-3 methyl 2-(2,3-difluoro-6-nitrophenyl)-3-oxobutanoate 

Downstream Products

• 649736-31-2 1-(2-fluoro-3-hydroxy-6-nitrophenyl)propan-2-one 

Relevant articles and documents

CHEMICAL PROCESS

The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline.