1022154-82-0 Usage
Uses
Used in Pharmaceutical Research:
1-(4-(1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethan-1-one is used as a key intermediate for the development of new drugs due to its potential as an analgesic, anti-inflammatory, and anti-cancer agent. Its diverse pharmacological properties make it a promising candidate for various therapeutic applications.
Used in Agrochemical Development:
In the agrochemical industry, 1-(4-(1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethan-1-one is used as a building block in the synthesis of various organic compounds with potential biological activities. Its versatility in chemical synthesis contributes to the development of new agrochemicals with improved efficacy and selectivity.
Used in Medicinal Chemistry:
1-(4-(1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethan-1-one plays a crucial role in the field of medicinal chemistry and drug discovery. Its unique structure and properties allow for the design and synthesis of novel compounds with potential therapeutic benefits, making it an important tool in the search for new treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1022154-82-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,2,1,5 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1022154-82:
(9*1)+(8*0)+(7*2)+(6*2)+(5*1)+(4*5)+(3*4)+(2*8)+(1*2)=90
90 % 10 = 0
So 1022154-82-0 is a valid CAS Registry Number.
1022154-82-0Relevant academic research and scientific papers
Discovery of MK-5046, a potent, selective bombesin receptor subtype-3 agonist for the treatment of obesity
Sebhat, Iyassu K.,Franklin, Christopher,Lo, Michael M.-C.,Chen, David,Jewell, James P.,Miller, Randy,Pang, Jianmei,Palyha, Oksana,Kan, Yanqing,Kelly, Theresa M.,Guan, Xiao-Ming,Marsh, Donald J.,Kosinski, Jennifer A.,Metzger, Joseph M.,Lyons, Kathryn,Dragovic, Jasminka,Guzzo, Peter R.,Henderson, Alan J.,Reitman, Marc L.,Nargund, Ravi P.,Wyvratt, Matthew J.,Lin, Linus S.
supporting information; experimental part, p. 43 - 47 (2011/04/17)
We report the development and characterization of compound 22 (MK-5046), a potent, selective small molecule agonist of BRS-3 (bombesin receptor subtype-3). In pharmacological testing using diet-induced obese mice, compound 22 caused mechanism-based, dose-
Substituted inmidazoles as bombesin receptor subtype-3 modulators
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Page/Page column 32, (2010/02/17)
Certain novel substituted imidazoles are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of BRS-3, such as obesity, and diabetes.
