1022170-04-2Relevant articles and documents
Silver-catalyzed spirolactonization: first synthesis of spiroisoindole-γ-methylene-γ-butyrolactones
Rammah, Mohamed M.,Othman, Mohamed,Ciamala, Kabula,Strohmann, Carsten,Rammah, Mohamed B.
, p. 3505 - 3516 (2008/09/21)
γ-Acetylenic carboxylic acids are cyclized to spirolactones under mild conditions, in the presence of Ag2CO3 catalyst. The corresponding spiro-5-alkylidene-γ-butyrolactones were isolated in high yields, and this process constitutes an easy and efficient route to analogous structures of natural products of biological interest.
Halolactonization of γ-acetylenic acids: systhesis of novel spiroisoindole halobutyrolactones
Rammah, Mohamed M.,Othman, Mohamed,Msaddek, Moncef,Rammah, Mohamed B.
scheme or table, p. 1971 - 1981 (2009/04/06)
γ-Acetylenic carboxylic acids are cyclized to spirohalo butyrolactones, in the presence of NBS or NIS and K2CO3. The corresponding 5(E)-haloalkylidene-spirobutyrolactones were isolated in high yields, and this process constitutes an easy and efficient route to analogous structures of natural products of biological interest.
