1022186-29-3Relevant academic research and scientific papers
Synthesis and insect attractant activity of fluorine-containing Pinus diterpenic amides and imines
Rao, Xiaoping,Song, Zhanqian,Han, Zhaojiu,Jiang, Zhikuan
, p. 851 - 860 (2009)
A series of fluorine-containing Pinus diterpenic amides and imines have been synthesised and their structures were confirmed by elemental analysis, IR, 1H NMR spectroscopy and single crystal X-ray diffraction. Their insect attractant activity to Spodoptera litura were screened by leaf plate method; the results indicated that most fluorine-containing dehydroabietic amides and imines exhibited attractive activity to S. litura, in which dehydroabietic p-trifluoromethyl amide (A6) exhibit seven times the attractive rate compared with blank at the concentration of 0.01 g mL-1. The fluorine moiety fused to the benzene ring results in decreased attractive rates for amides except (A6), while the effects of fluorine result in increased attractive rates for diterpenic imines.
Synthesis and antitumor activity of novel α-aminophosphonates from diterpenic dehydroabietylaminer
Rao, Xiaoping,Song, Zhanqian,He, Ling
, p. 512 - 516 (2008/12/22)
A series of novel α-aminophosphonates were synthesized from diterpenic dehydroabietylamine, and their structures were characterized by IR, 1H NMR, and 31P NMR spectroscopy. Their antitumor activities against SMMC7721 liver cancer cells were evaluated by the MTT method. Compounds 4 and 6 exhibited higher activities even at very low concentrations, and the inhibition ratios reached 75% and 79% at 0.1 μM, respectively. The inhibition ratio of compound 9 reached 99% after 72-h incubation. α-Aminophosphonates with a fluorine atom and a nitro group fused to the benzene ring exhibited higher activities.
