102219-60-3Relevant academic research and scientific papers
SYNTHESIS OF AMINO SUGARS VIA ISOXAZOLINES. THE CONCEPT AND ONE APPLICATION: NITRILE OXIDE/FURAN ADDUCTS
Mueller, Ingrid,Jaeger, Volker
, p. 4777 - 4780 (1982)
Aliphatic nitrile oxides cycloadd to furans to afford amino sugar precursors 1.Oxidation by m-chloroperbenzoic acid and/or LiAlH4 reduction give rise stereoselectively to derivatives of the xylo and ido series, 2 - 4, with 3 to 5 adjacent chira
SYNTHESIS OF AMINO SUGARS VIA ISOXAZOLINES. NITRILE OXIDE-FURAN ADDUCTS AS KEY INTERMEDIATES IN THE ISOXAZOLINE ROUTE TOWARDS NOVEL AMINO SUGAR DERIVATIVES
Jaeger, Volker,Mueller, Ingrid
, p. 3519 - 3528 (2007/10/02)
New variations for 1,3-dipolar nitrile oxide cycloadditions to reluctant dipolarophiles furan and 2-methylfuran are presented.The furoisoxazoline adducts 6 and 7 are shown to represent highly advanced, yet versatile precursors for derivatives of novel C6 and C7 amino sugar derivatives, accessible by subsequent highly stereoselective modification (addition of HO/OCH3 or HO/OH) and/or LiAlH4 reduction.
